changes in salivary gland function following radioiodine therapy of thyroid diseases: a comparison of high-dose therapy for thyroid cancer and low-dose therapy for benign thyroid disease
نویسندگان
چکیده
introduction: high-dose radioactive iodine therapy in differentiated thyroid cancer (dtc) may adversely affect the salivary gland function. this study is aimed to evaluate the effect of radioactive iodine (rai) with dose of 100 mci in dtc patients compared to lower doses of less than 30 mci in hyperthyroid cases. methods: fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years were enrolled in the study. twenty seven hyperthyroid cases received less than 30 mci of i-131 for the treatment, and 27 dtc patients were treated with 100 mci of i-131. all patients underwent tc-99m pertechnetate scintigraphy before and three months after radioiodine therapy. salivary gland excretion fractions (ef) were compared between groups. a decrease of more than 5% in ef was considered significant. results: the total frequency of salivary dysfunction was 41.7%. in patients received a dosage of 100 mci of i-131, this frequency was 49.1%, while with less than 30 mci, it was 34.3% (p
منابع مشابه
Changes in salivary gland function following radioiodine therapy of thyroid diseases: A comparison of high-dose therapy for thyroid cancer and low-dose therapy for benign thyroid disease
Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years w...
متن کاملChanges in salivary gland function following radioiodine therapy of thyroid diseases: A comparison of high-dose therapy for thyroid cancer and low-dose therapy for benign thyroid disease
Introduction: High-dose radioactive iodine therapy in differentiated thyroid cancer (DTC) may adversely affect the salivary gland function. This study is aimed to evaluate the effect of radioactive iodine (RAI) with dose of 100 mCi in DTC patients compared to lower doses of less than 30 mCi in hyperthyroid cases. Methods: Fifty four patients (13 men and 41 women) age: 42.3±14.3 (21-71) years we...
متن کاملRadioiodine therapy effects on salivary gland function in patients with differentiated thyroid cancer [Persian]
Salivary gland involvement is one of the radioiodine therapy complications. Salivary gland scintigraphy in quantitative mode can accurately evaluate salivary gland function. Methods: Salivary gland scintigraphy was performed with Tc-99m Pertechnetate, at the time of iodine therapy as a basic study and then 3 weeks and 3 months afterwards. Ejection Fraction (EF) of parotid and submandibula...
متن کاملDetermination of absorbed dose of organs (thyroid, sternum, cervical vertebra) in thyroid cancer patients following radioiodine therapy
Introduction: In patients with thyroid carcinoma, radiation absorbed doses of the thyroid and surrounding tissues is important to weigh risk and benefit considerations. In nuclear medicine, the accuracy of absorbed dose of internally distributed radionuclides is estimated by different methods such as MIRD and direct method using TLD. The aim of this study is using T...
متن کاملradioiodine therapy effects on salivary gland function in patients with differentiated thyroid cancer [persian]
salivary gland involvement is one of the radioiodine therapy complications. salivary gland scintigraphy in quantitative mode can accurately evaluate salivary gland function. methods: salivary gland scintigraphy was performed with tc-99m pertechnetate, at the time of iodine therapy as a basic study and then 3 weeks and 3 months afterwards. ejection fraction (ef) of parotid and submandibular glan...
متن کاملdetermination of absorbed dose of organs (thyroid, sternum, cervical vertebra) in thyroid cancer patients following radioiodine therapy
introduction: in patients with thyroid carcinoma, radiation absorbed doses of the thyroid and surrounding tissues is important to weigh risk and benefit considerations. in nuclear medicine, the accuracy of absorbed dose of internally distributed radionuclides is estimated by different methods such as mird and direct method using tld. the aim of this study is using tld and a phantom to determine...
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عنوان ژورنال:
iranian journal of nuclear medicineناشر: tehran university of medical sciences
ISSN 1681-2824
دوره 23
شماره 1 2014
کلمات کلیدی
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